intracellular glutathione transporter compartmentalization. Glutathione synthesis The Multifaceted Role of Glutathione

10.1038/nature13909 Nature 9 DabrowskaD.JablonskaE.GarleyM.Ratajczak-WronaW.IwaniukA

Dai ZT, Xiang Y, Duan YY, Wang J, Li JP, Zhang HM, Cheng C, Wang Q, Zhang TC, Liao XH

Notably, the accumulation of genetic mutations (e.g., point mutations, inversions, translocations, deletions, and polyploidy) drives the malignant transformation of cancer cells and facilitates the acquisition of cancer-specific hallmarks, including cell immortality, apoptosis inhibition, drug resistance, angiogenesis, invasiveness, and the activation of metastatic processes [3,4,5,6]

Metabolic adaptation of lymphocytes in immunity and disease

Western blot analysis SDS-PAGE and Western blot analysis were performed as described [18]