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Nrf2, the master regulator of antioxidant response, showed approximately 70% decreased expression and activity in CF cells compared to normal controls (Chen et al., 2008)

The upper result, plus the evidence that the ratio of IL18R1/CXCR3 is six fold more in the ovary than in the tumor, supports that IL18R1 is surplus and CXCL10 can directly bind to IL18R1 (Supplementary Fig

GR activity was reduced by exercise in a time-dependent manner, while no changes were observed in GPx and GST activities during time

A recent CDC study (Smith et al 2011) carried out a genome-wide mapping of gene SNPs and gene expression in 40 CFS patients and 40 controls