glutathione peroxidase gsh-px คอ The reaction. a The catalytic triad that is Glutathione peroxidase 4: a new

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However, in cancer cells, dysregulation of the PI3K/AKT/mTOR pathway drives reprogramming of lipid metabolism, which is manifested by abnormal enhancement of FAO, which not only provides ATP for tumors, but also inhibits apoptosis and regulates redox homeostasis, which ultimately leads to the development of tumor drug resistance [36, 188, 189]