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Prevalence of mental disorders among people with opioid use disorder: a systematic review and meta-analysis

These findings might be partly explained by short follow-up, different doses of l-carnitine, and the inclusion of low-quality trials without randomization and blinding [14, 15]

The migraine group had a higher proportion of females (75.7%) compared to HC (50.0%) and TTH (63.2%), consistent with known epidemiology, though this difference did not reach statistical significance ( p = 0.144)

While PT-141 does not directly act on dopamine receptors, melanocortin receptor activation in the hypothalamus appears to influence dopaminergic neurotransmission