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The level of MDA is a good marker of oxidative stress and the antioxidant/prooxidant status of patients suffering from cancer

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MnO x nanospikes, as TME-responsive nano-adjuvants and immunogenic cell death drugs, were also designed for cancer nanovaccine-based immunotherapy ( 2 and Fe 3 O 4 were co-loaded on to dendritic mesoporous silica NPs, researchers showed that these particles can achieve tumor specialized localization and induction of Fenton reaction, thus triggering ferroptosis (Li and Rong, 2020)

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