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Adair-Kirk TL, Atkinson JJ, Griffin GL, Watson MA, Kelley DG, DeMello D, Senior RM, Betsuyaku T: Distal airways in mice exposed to cigarette smoke: Nrf2-regulated genes are increased in Clara cells

The inflammasome within macrophages exacerbates the advancement of AD, while the absence of NLRP3 mitigates oxidative stress and regulates macrophage polarization