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However, the potential immunosuppressive effects of JAK inhibitors also pose challenges, particularly in immunocompromised individuals or those with concurrent infections

In the cocaine-dependent patients, glutamate levels were normalized by a single oral administration of NAC (2.4 g) [128]

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Multiple organ failure including sepsis-induced cardiac dysfunction seem to be the result of numerous factors as overwhelming inflammation and nitric oxide synthesis impairment associated with mitochondrial dysfunction and increased oxidative stress (Cecchini and Cecchini, 2020)