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Targeting the GLP-1/GLP-1R axis to treat osteoarthritis: A new opportunity

Ex vivo experiments using precision-cut lung slices from IPF patients and mouse models further confirmed saracatinibs ability to downregulate fibrotic genes, reduce collagen accumulation, and decrease -SMA-positive areas

Heres the critical trade-off every pharmacist needs to explain: Key Counseling Point: An irAE often means the patient's immune system is "waking up" to fight the cancer