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It increases antioxidants, decreasing inflammatory markers, indicating its potential use against cystitis ( Silybum marianum Silymarin is a flavonolignan compound derived from the seeds of the Silybum marianum known as the milk thistle and has been used in Europe as well as Asia for the treatment of liver diseases (Lorenzo et al., 2020)

The heterogeneous manifestations of HE vary not only between patients but also longitudinally for an individual patient

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In Europe and the United States, approximately 2.5 million people develop TBIs each year (99)