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The vagus nerve connects the brain to the heart and gut

Studies have shown that cells dependent on mitochondrial oxidative phosphorylation for energy are 1,000-fold more sensitive to copper ion carriers than glycolysis-dependent cells (190)

Several studies demonstrated that RIPK3 expression was significantly increased in the livers of mice fed long-term ethanol and in liver biopsies of patients with ALD (Roychowdhury et al., 2013

Besides, in the retina of Rras knockout mice, hypoxia can cause early pathological vascular hyperpermeability via hypoxic cell injury/death (ferroptosis), indicating an important role of ferroptosis in ischemic retinal diseases (Vahatupa et al., 2023)

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