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Over 42 days, the ethanol group received 20% ethanol in their drinking water, while losartan was administered intraperitoneally at doses of 1 mg/kg and 3 mg/kg to the treatment groups.The results demonstrated that losartan significantly reduced oxidative stress markers, evidenced by decreased levels of malondialdehyde and increased total thiol levels in renal tissues

It reduces shelf life from 28 days to under 72 hours and increases contamination risk with repeated needle entry

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The resulting product was ground to a fine powder using a mortar and pestle