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Both culture-based and sequencing studies have identified a shared core microbiota across teat skin, teat canal, and mammary gland cistern, dominated by non- aureus Staphylococci (NAS) and Corynebacterium , and including some environment-associated taxa such as Clostridiaceae and Acinetobacter 187 , providing microbial evidence for a continuous skinmammary axis

Nitric Oxide 2(5):324336

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The study, published in Nature Metabolism, found metformin slows mitochondrial energy production in gut cells, forcing the intestine to metabolize extra sugar