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2 In the following decades, Christian de Duves discovery of lysosomes and his subsequent identification of autophagy defined intracellular degradation and recycling pathways as central elements of proteostasis

That risk is higher with kidney disease or specific medications

However, a glutathione deficiency can disrupt normal bodily functions

Abstract Ototoxicity, the property of certain drugs to cause hearing loss, is a significant concern in medical treatments, particularly with the use of chemotherapeutic agents like cisplatin and aminoglycosides