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Several commenters criticized the lack of adequate risk adjustment for social and demographic factors, noting that hospitals serving higher-risk, underserved, or rural populations could be unfairly affected despite delivering high-quality care

41 Noninvasive serological tests, such as tests for eosinophils, 42 calprotectin, 43 and C-reactive protein, 44,45 are helpful in the diagnosis of UC

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Disadvantages: Expensive ($500-$1500 per 4-week course)

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