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Several studies (Table 3) have shown that LA significantly reduces body fat mass, hepatic clearance of TG-rich lipoproteins, and lipid droplets through upregulating the expression levels of hepatic lipolytic enzymes (ATGL, acyl-CoA thioesterase [Acot1], Acot2, Acsf2, and Crat) and downregulating the expression levels of liver lipogenic enzymes (patatin-like phospholipase domain protein [Pnpla3], Pnpla5, Elovl6, Acly, sn-glycerol-3-phosphate acyltransferase 1 [Gpat], Aacs, FASN, ACC, and SCD-1)

Unfortunately, glutathione levels decline with age, most specifically due to poor nutrition, stress, and to toxins from the environment

Batra P, Sharma AK

Finally, SOD activity was significantly decreased in the SCI group ( P = 0.046) compared with that in the control group

From the perspective of clinical application prospects, the application prospects of tissue engineering for the treatment of intervertebral disc degeneration are broad