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The Gsta4 effect on apoptosis during adult OL differentiation was corroborated in vivo in both lysolecithin-induced demyelination and experimental autoimmune encephalomyelitis models, where Casp8 activity was reduced in Gsta4-overexpressing OLs

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Glutathione, known as the bodys master antioxidant, is made up of amino acids glycine, cysteine and glutamic acid

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