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54,55 Moreover, methylation loss at specific sites in tumor cell genomes, particularly in oncogene promoter regions, and extensive demethylation in DNA repeat sequences, undermines chromosome stability, facilitating tumor development

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Here we break down some of the key findings: Improved Insulin Sensitivity and Metabolic Health One of the first major MOTS-c studies showed a dramatic impact on metabolism

10.1172/JCI140100 34 EvasonK