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The capacity of AML cells to detoxify lipid peroxides by increasing their cystine uptake to maintain major antioxidant molecule glutathione biosynthesis after exposure to APR-246 may be a key determinant of sensitivity to this compound

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The U-HPLC system was coupled to a 6490 triple quadrupole MS (Agilent Technologies), equipped with electrospray ionization source, performed in negative ion mode

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Science 290: 15711574 Weissman JS, Kim PS (1993) Effcient catalysis of disulphide bond rearrangements by protein disulphide isomerase

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How Food Slows Alcohol Absorption and Lowers Peak BAC There are two distinct biological mechanisms through which food reduces peak BAC

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