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Description

Kraus et al., Nature Medicine show that NNMT inhibition can increase energy expenditure and improve metabolic health without altering diet or activity

PMC 6176737

Oxidative stress in urine in MHL subgroup (HF, HP) was much higher than MUO subgroup (HF, HP) at 360 mins after the meals ( P 0.05)

doi: 10.1038/ncb2738 20 HardingH

Traditional therapies primarily rely on RAAS blockers, such as ACE inhibitors or ARBs, which can slow albuminuria progression but offer limited efficacy in late-stage DN and fail to reverse renal fibrosis (Samsu, 2021)