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For instance, Fisher et al.[48] found up to 7-fold differences in the rates of APAP glucoronidation in a sample of 20 human livers, and Court et al.[54] found 15-fold inter-individual variability in APAP glucoronidation rates in liver microsomal fractions

Perinatal exposure to low-dose methoxychlor impairs testicular development in C57BL/6 mice

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However, given the dose-dependent side effects of CAF, such as CAF tolerance, restlessness, and gastrointestinal discomfort, et al., we did not attempt to use higher dosages to test whether statistically significant changes could be observed in the measured indexes