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Wang J, Zhang H, Kaul A, Li K, Priyandoko D, Kaul SC, et al

For patients with Brugada syndrome, Quinidine is an alternative to implantable cardioverter-defibrillator (ICD) placement (66) This class has also shown utility in individuals with short QT syndrome experiencing recurrent ventricular arrhythmias (VAs), reducing the frequency of ICD shocks in these patients (66)

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Also, treatment with Vardenafil has been shown to decrease DNA damage and oxidative stress, as well as to increase cGMP levels in aortic walls [24]