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Description

Ammonia readily crosses the blood-brain barrier and is thought to inhibit glutamate uptake, thereby increasing extracellular glutamate concentrations in the brain and resulting in activation of NMDA receptors

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A 2011 clinical study (phase III trial) has shown that a vaccine targeting a unique molecular structure on certain lymphoma cells improved disease-free survival in follicular lymphoma patients who were already in a minimal residual disease state (ie, had a complete response after 6 to 8 months of combination chemotherapy) (Schuster 2011)

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