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That plan may also include strengthening work, activity modification, weight management where appropriate, pain relief, bracing or other injection treatments

AOD9604, when injected in saline, may be rapidly cleared from the joint due to uptake into local circulation, limiting its therapeutic effects

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Occasionally, signs of acute toxicity may be absent for 1248 hours following administration, after which a critical phase may develop, characterised by pulmonary oedema, vasomotor collapse, cyanosis, acute hepatic failure, coma, and death of the animal