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Immunosuppressive effects of sialostatin L1 and L2 isolated from the taiga tick Ixodes persulcatus Schulze

In contrast, knockdown of TfR1 in BJ-TERT/LT/ST/RAS V12 cells partially inhibited ferroptosis induced by erastin [10] Related studies have confirmed that the JNK/p38MAPK pathway plays a role in erastin-induced ferroptosis in HL-60/NRAS Q61L cells and that activation of JNK/p38MAPK, an upstream signaling pathway of TfR1, can upregulate the expression level of TfR1 [25]

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DNA damage is the main cause of several diseases like cancer