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doi: 10.1038/s41401-025-01598-4 56 WangYNLiXJWangWFZouLMiaoHZhaoYY

Interestingly, in malaria, heme oxidation products derived from RBC lysis have deleterious effects on RBC deformability and were proposed to be responsible for changes in blood flow and microcirculation (141)

Also, mice carrying a genetic mutation that lack one of the igf1r alleles ( igf1r +/ ) show a 10 % reduction in post-natal growth, insulin resistance and glucose intolerance [237]

Conversely, Category G89 codes will not be listed first if the diagnosis is specifically for the underlying condition causing the pain, i.e., spinal fusion