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WL was the lead investigator and reviewer for the metallothionein section

The H 2 O 2 concentration drives the redox balance in the cell from GSH toward GSSG (see Figure 1) and the increased concentrations of H 2 O 2 and GSSG can modulate many enzymes in one-carbon metabolism (see Section E)

The role of the CPT family in cancer: searching for new therapeutic strategies

This process suggests that increased lactate concentration in the brain following TBI is associated with changes in histone lactylation levels and the regulation of gene expression, such as BDNF (Figure 4), thereby exerting neuroprotective and regenerative effects

As these technologies mature, they could offer even more nuanced choices for researchers, further complicating (or simplifying, depending on your perspective) the decision-making process