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Los niveles de GSH disminuidos juegan un importante rol en la iniciacin del proceso de apoptosis y la disminucin drstica de los niveles de GSH especialmente a nivel mitocondrial, llevan a la disfuncin mitocondrial y sobreviene la muerte celular (19)

All these mechanisms lead to MS-like motor symptoms observed in patients with Cbl deficiency such as subacute degeneration of the spinal cord [84]

Its potential against acute and latent M.tb infections is still under investigation, and small-scale clinical trials may be necessary to assess its anti-TB efficacy either as a monotherapy or in combination with other anti-TB drugs