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Apply peel with brush, start applying from the forehead up to the neck, application time should not be more than 20 seconds Keep peel for 3-7 minutes depending on your skin sensitivity

Annu Rev Genet 40: 409448

Lands WE

Exposure of human melanocytes to UVB twice and subsequent incubation leads to cellular senescence and senescence-associated pigmentation through the prolonged p53 expression

These conditions are driven by oxidative stress and mitochondrial dysfunction, which lead to the degeneration of retinal cells, including RGCs and photoreceptors [57]