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Males and females were treated with 20 mM BSO (19176, Sigma-Aldrich) in the drinking water starting at 21 days of age, immediately after weaning

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However, another study using rats showed that protein levels of NAMPT, COX1, and PGC-1a were unchanged in skeletal muscles after 4 weeks of treadmill exercise, and NAD + levels or other mitochondrial readouts were not included 308

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Each member of these classes of drugs is designed to reduce AT 1 receptor activation and control hypertension