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Chronic deficiency may elevate the baseline risk of ischemia by impairing vascular elasticity (via compromised LOX function) and promoting platelet aggregation [162]

doi:10.3389/fphar.2021.720873 39

The cue system (for Cu e fflux) transcriptionally activates both plasmid- and chromosomally-encoded copper homeostatic systems in response to intracellular Cu + sensing through CueR, a MerR-family metalloregulatory transcriptional activator (Petersen and Moller, 2000

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