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Reconstituting a peptide vial requires converting between milligrams, micrograms, millilitres, and syringe units a process that often leads to confusion and mistakes

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How to reduce pain caused by injection technique Assess the patients experience of injections and explain the reason for the injection Use the correct technique, and length and gauge of needle Rotate injection site to prevent indurations or abscesses Explain the benefits of the injection to the patient Position the patient so the muscles are relaxed Use distraction Insert and remove the needle smoothly and quickly Hold the syringe steady during the procedure Inject medication slowly but smoothly Source: Adapted from Lister et al (2020) Evidence base The procedure for IM injection has been discussed widely in the literature but there are concerns that nurses are still performing outdated and ritualistic practice relating to site selection, aspirating back on the syringe (Greenway, 2014) and skin cleansing

EHD proteins are associated with tubular and vesicular compartments and interact with specific phospholipids

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