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Frontiers HDAC8 impairs tight junctions in allergic rhinitis through Smad7 deacetylation Dihexa (also known as PNB 0408) is an experimental small molecule derived from angiotensin IV. It was engineered to cross the bloodbrain barrier and has shown synaptogenic effects in preclinical models. The often quoted Dihexa 1401708 83 5 dihexa human trials Dihexa (also known as PNB 0408) is an experimental small molecule derived from Full article: A patent review of histone deacetylase 8 (HDAC8) inhibitors (2013present)
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