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Any combination of treatments should be discussed with and supervised by a qualified medical provider before starting.

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Another contribution of hypoxia to tumor immune escape that is mediated by HIF-1a is a decrease in cancer cell susceptibility to T-cell-mediated killing (Noman et al., 2009)

Wang, W.-z, Liu, C., Luo, J.-q, Lei, L.-j, Chen, M.-h, Zhang, Y.-y, Sheng, R., Li, Y.-n, Wang, L., Jiang, X.-h, Xiao, T.-m, Zhang, Y.-h, Li, S.-w, Wu, Y.-x, Xu, Y., Xu, Y.-n, & Si, S.-y