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Includes both toxicokinetics and toxicodynamics, as well as technological improvements that will help in the characterisation of this field

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Moreover, p53 deficiency in committed skeletal muscle cells decreases their ability to differentiate into BAT

Based on potential binding regions predicted by JASPAR database, we designed specific primers targeting the binding site between c-Myc and the miR-29b-3p promoter (Table S2)

Human studies have shown that lowered pH levels can also negatively affect the excitation-contraction coupling in the skeletal muscle [38,41]