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(Han and Smith, in vitro studies performed by our research group have shown that co-administration of conventional chemotherapeutic agents with antioxidants such as melatonin enhances chemotherapeutic-induced cytotoxicity and apoptosis in different cancer cell lines (Uguz et al., 2012

These findings imply that retromer binds cooperatively to both motifs for efficient LYSET recycling to the Golgi (Fig

Metformin, which is well-tolerated due to extensive clinical experience in diabetes management, has shown promising epidemiological associations with reduced cancer incidence and improved outcomes in some studies

Mobile phase A and B was 0.2% (v/v) AA in water (Optima grade, Fisher Scientific, USA) and 0.2% (v/v) AA in LC-MS grade acetonitrile (Honeywell, USA), respectively

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