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These studies have led to significant additional insight into cellular signaling events driving hepatocyte death and liver injury after APAP overdose and will be reviewed in this article

Mycoses 62 , 328335 (2019)

Ravikumar et al., 2010) reveal abnormal cleavage of PICALM in AD brains, with significantly reduced 75 kDa PICALM levels, disrupted cathepsin D (Cath D) processing, and impaired lysosomal function, leading to autophagy deficits and inhibited Tau degradation