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The IC50 of paracetamol on HepG2 cells was reduced from 1.389 mM to 0.995 mM after addition of BSO

7.5 Critical discussion of translational challenges The translation of ferroptosis-targeting agents for AD faces multiple interconnected challenges, with BBB penetration, off-target effects, long-term safety, and perturbations of iron metabolism and immune function being the most prominent