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Melatonin is derived from serotonin, a neurotransmitter that originates from the amino acid tryptophan

4.5 Copper Copper (Cu) plays two main roles: it promotes melanogenesis and provides physiological protection against oxidative stress by participating in the destruction of free radicals through the formation of superoxide dismutase, which catalyses the dismutation of reactive oxygen species to oxygen (O 2 ) or H 2 O 2

Further to its role in detoxification, GSTP1 has a myriad of other diverse and important cellular functions [610]

The primary objective of ongoing therapeutic trials is to reverse this dysfunction (Deng et al

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