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Acta Med Scand (1968) 184(4):24758.10.1111/j.0954-6820.1968.tb02452.x 4 WitheyJLJonesJHKilpatrickGS

In this section, we present a summary of the mechanisms and critical regulators associated with ferroptosis from various aspects including iron metabolism, SystemX c /glutathione axis, and lipid peroxidation regulation (Figure 1)