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The mode of NOX-2 inhibition seems to stem from an inhibition of platelet-derived growth factor (PDGF)-mediated NAD(P)oxidase activation (Ten Freyhaus et al., 2006)

Exp Cell Res 319(9):13171323 Kondo A, Tokuda H, Mizutani J, Matsushima-Nishiwaki R, Kozawa O, Otsuka T (2012) Wnt3a upregulates prostaglandin F2-stimulated vascular endothelial growth factor synthesis in osteoblasts

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