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Although several theories with empirical support tackle the point, the causes of BIPN are multifactorial and not fully understood, it remains a potentially persistent adverse event that can lead to long-term objective neurological dysfunction (Li et al., 2020), thereby reducing the quality of life, weakening physical function, causing delays or dose reductions in chemotherapy, and in some cases even interrupting treatment, imposing a huge economic burden (Selvy et al., 2021)

Mohamed 1 , Hussien Osama 1 , Muataz Kashbour 2 , Ahmed Amin 3 1 Faculty of medicine, Mansoura University, Mansoura, Egypt, Mansoura, Egypt, 2 Diagnostic Radiology Department, National Cancer Institute, Misrata, Libya, Misrata, Libya, 3 Faculty of Medicine, Al-Azhar University, Cairo, Egypt, Cairo, Egypt Background and Aims: Cerebral edema is a serious complication of ischemic and hemorrhagic strokes, contributing to increased mortality and poor clinical outcomes

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