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Long journeys, disrupted sleep, time-zone changes, and irregular eating habits may lead to fatigue

Folic Acid Caution: High doses of folic acid can mask the blood-related symptoms of vitamin B12 deficiency, but do not protect against nerve damage

Therefore, it is tempting to speculate that the biphasic decline in serum IgG reflects an initial, rapid decline in short-lived PBs, followed by a second, slower decline in long-lived PCs

Riboflavin is an antioxidant

Injectable hydroxocobalamin is the standard UK treatment for confirmed B12 deficiency, particularly when neurological symptoms are present or absorption is impaired, providing rapid correction with doses given initially three times weekly then every two to three months