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For example, a person who has a potassium deficiency may suffer chronic headaches

However, the generation of substrate GSH is tightly regulated by system x c

Selective transport of blood-borne interleukin-1 into the posterior division of the septum of the mouse brain

With modern lifestyle, liver disease has become common worldwide

The frequency of these events varies by ethnicity, with Asians having the highest frequency of loss-of-function mutations (50%), and Whites the least (9%) (Nakajima et al., 2006