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investigated the effectiveness of acetyl-l-carnitine in 28 patients with painful radiculopathies and neuropathies, including 17 with chronic lumbar radiculopathy, unresponsive/poorly responsive to previous treatment ( 30% pain relief) [50, 51]

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Munc13-4 was first identified as a docking and fusion regulator in secretory pathways of several cell types 17,18,19,20 , where it controls exocytosis in hematopoietic cells through interactions with Rab27a (ref