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While DAO and HNMT are the primary enzymes for histamine degradation, the liver processes the downstream metabolites and crucially, it regulates oestrogen, which has a critically important and bi-directional relationship with histamine

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Disclosures: Priyata Dutta: Nothing to Disclose, Robert Fontana: kezar pharmaceuticals: Grant/Research Support, Takeda Pharmaceuticals: Grant/Research Support, Nikhilesh Mazumder: Nothing to Disclose 1361 THE PATIENT AND KIDNEY GRAFT OUTCOMES OF SAFETY NET KIDNEY TRANSPLANTS ARE SIMILAR TO KIDNEY TRANSPLANT RECIPIENTS WITHOUT A PREVIOUS LIVER TRANSPLANT: A RETROSPECTIVE UNOS DATABASE ANALYSIS Mohanad Awadalla 1 Yong-Fang Kuo 2 Ashwani Singal 3 , 1 Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, 2 UTMB Galveston, 3 University of Louisville Background: The Organ Procurement and Transplantation Network (OPTN) implemented the allocation policy in 2017 to standardize the approach to simultaneous liver-kidney (SLK) listing and optimize the use of deceased donor kidneys

Kim AE, Lee IT, Dokras A, LIMITED ADOPTION OF CURRENT POLYCYSTIC OVARY SYNDROME (PCOS) RELATED INFERTILITY TREATMENT GUIDELINES BY REPRODUCTIVE ENDOCRINOLOGY AND INFERTILITY (REI)