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MOTS-C, if included, at 10mg injected subcutaneously two to three times per week

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However, its oral bioavailability (8%) was markedly lower than that observed after intravenous dosing (75%), indicating that approximately 67% of the orally administered dose is lost during gastrointestinal absorption (120)

Specifically, significantly elevated levels of proinflammatory cytokines, including TNF-, IL-1, and IFN-