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Administration of low concentrations of luteolin (15 M) resulted in enhanced cell viability, inhibition of lactate dehydrogenase (LDH) release, and a reduction in levels of IL-1, concomitantly modulating the expression of genes pertinent to PD: specifically, an elevation in Park2, a reduction in Lrrk2, and an enhancement of Nrf2 and Trx1 expression

Later in the infection, the combination of signals and pathways induced for bacterial internalization may promote a localized loss of barrier function, allowing the paracellular route to occur, making bacterial internalization a requisite step for further invasion

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The expected increase of m / z was only observed in the matrix-assisted laser desorption ionization (MALDI) spectra of the wild-type enzyme, in line with an S -glutathionylation at C13 (Extended Data Fig