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The mechanistic rationale for adjunctive use is strong

The cellular modulation and protein replacement therapeutic strategies involve mRNAs that encode a functional protein, which can be expressed in the target cell as an endogenous protein, a functional foreign protein or proteins used for gene editing or cellular modulation (Figure 7

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Retinal detachment and injury recovery Mechanism: Physical separation of retina from underlying RPE and choroid, cutting off blood supply and causing photoreceptor death within hours to days