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doi: 10.1007/s10815-024-03314-3 36 AndlibNSajadMThakurSC

, Koudela M., Chmelarova H., Hajslova J., and Novotny C

Taken together, GLP-1based and dual GLP-1/GIP agonists represent a biologically plausible and clinically feasible strategy for repurposing as adjunctive neuroprotective therapies in PD, although further preclinical and clinical studies are needed to define their optimal dosing, treatment duration, and combinational approaches to ensure sustained neuroprotection (Figure 2)