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Inositol and choline further enhance this process by contributing to lipid transport and energy regulation within cells

In Phase 2, the escalation period was relatively rapid, contributing to higher rates of gastrointestinal intolerance during the first weeks of treatment

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It demonstrates potent anti-glioblastoma activity by: (1) blocking tumor invasion and cytokinesis (inducing polyploidy), (2) disrupting mitochondrial dynamics to elevate ROS and trigger ferroptosis, and (3) sensitizing tumors to radiotherapy/kinase inhibitors via ROS-driven PDGFR/mTOR pathway activation